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Protein Crystallization Technology


The protein crystallization technique is traditionally used only for the determination of the three-dimensional structure of a protein. At ProCrysta, we have mastered the art of macromolecules crystallization to provide innovative purification and formulation services for large molecules.  ProCrysta’s proprietary crystallization and formulation technology brings many benefits to macromolecules including improved purity, stability and delivery options. Crystallization technology is applicable to many classes of therapeutic proteins. ProCrysta team has crystallized over 30 proteins from various classes including.

  • Enzymes
  • Hormones
  • Monoclonal and Polyclonal Antibodies
  • Peptides
  • Pegylated proteins
  • Fusion proteins

Crystallization can be performed in reproducible and scalable manner to yield highly pure protein. Thus can be used in an industrial setting of protein manufacturing to reduce the cost. Protein crystals can also be utilized for high concentration formulations, insoluble formulations for catalytic reactions, long acting slower release formulations and for the stabilization of protein.


 

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